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Ajay Gupta

Ajay Gupta, MD

4.752 ratings, 5 reviews

Epilepsy NeurologyPediatric Epilepsy Neurology

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Highlights

Age Groups Seen

  • Child
  • Adolescent

Languages

  • Hindi
  • English

Gender

Male

About Ajay Gupta

Title

Section Head, Pediatric Epilepsy

Biography

Ajay Gupta, M.D. is the head of the section of Pediatric Epilepsy in the Epilepsy Center/Neurological Institute. He is Professor at The Cleveland Clinic Lerner College of Medicine, Case Western Reserve University. He is also the founder director of multidisciplinary Tuberous Sclerosis Program at the Cleveland Clinic.

Dr. Gupta is an expert in the field of childhood and adolescent epilepsy with emphasis on epilepsy surgery evaluation,management of complex childhood epilepsies, and neurocutaneous disorders such as Tuberous Sclerosis Complex and Sturge-Weber syndrome.  Dr. Gupta is also a skilled specialist in intra-operative neurophysiological techniques used during brain surgery to map regions of brain for critical function. His expertise attracts national and international consultations from families and practicing Neurologists who seek a second opinion for complex cases. Dr. Gupta is recognized by the Consumers' Research Council's 'Top Physicians' ofAmerica", Marquis’ "Who's Who in America", and the “Best Doctors in America”.

Dr. Gupta serves on the professional and scientific committees of the American Epilepsy Society, Child Neurology Society, and International League against Epilepsy. He serves on the editorial board of prestigious journals in the field, ‘Pediatric Neurology’ and Epilepsy Currents’. Dr. Gupta also works on the Professional and Scientific Board of the U.S. Tuberous Sclerosis Alliance. He serves on the peer-review panel of national and international journals in the field of epilepsy. He is a fellow member of the American Academy of Neurology, American Epilepsy Society, Child Neurology Society, International Child Neurology Association, and American Academy of Pediatrics.

Dr. Gupta has made innovative and pioneering contributions to advance the field of epilepsy surgery and treatment of epilepsy in children. A unique disease is named after him as a co-discoverer. His research interests are epilepsy surgery evaluation tools and outcomes, Tuberous Sclerosis Complex, and impact of epilepsy on brain development. He has authored over 150 original research articles, review papers in the peer-reviewed international journals, as well as textbooks. He is an avid mentor of resident and fellow trainees including visiting international fellows and junior faculty. Some of the trainees have received highly competitive awards and honors for their mentored research projects such as the Junior Investigator Research Awards at the American Epilepsy Society and Child Neurology Society, and Thomas Epilepsy award at the Cleveland Clinic Neuroscience Research competition. Many traineescurrently hold faculty positions at prestigious universities and hospitals in US and abroad. Dr. Gupta has also organized, chaired and directed many symposia, workshops, and seminars at the scientific national and international conferences. He is the Director of the annual Epilepsy Course organized at the Cleveland Clinic. He is an invited faculty to many national and international meetings to deliver lectures, workshops and skills training.

Dr. Gupta is board certified in the specialties of Pediatrics, Neurology/Child Neurology, EEG/Clinical Neurophysiology, and Epilepsy.

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Locations

  1. Cleveland Clinic Main Campus
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  2. Twinsburg Family Health and Surgery Center
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Education & Board Certifications

Education

  • Fellowship: Cleveland Clinic, 2003
  • Residency: Cleveland Clinic, 1998
  • Fellowship: Saint George's Hospital Medical School, University of London, 1996
  • Medical Education: Post Graduate Institute of Medical Education and Research, 1994
  • Medical Education: Punjab University Faculty of Medicine, 1991
  • Medical Education: Guru Nanak Dev University Faculty of Medicine, 1987
  • Undergraduate: Punjab University/DAV College, 1982

Board Certifications

  • Epilepsy: American Board of Psychiatry & Neurology, 2013
  • Clinical Neurophysiology: American Board of Psychiatry & Neurology, 2003
  • Neurology with Special Qualifications in Child Neurology: American Board of Psychiatry & Neurology, 2002

Professional Highlights

  • Head, Section of Pediatric Epilepsy, Cleveland Clinic
  • Professor, Cleveland Clinic Lerner College of Medicine of the Case Western Reserve University
  • Editorial Boards: Pediatric Neurology (current), Epileptic Disorders (past)
  • Contributing editor: Epilepsy Currents, contributing editor
  • Tuberous Sclerosis Alliance: Professional and Scientific Board
  • American Epilepsy Society: multiple professional and scientific committees
  • Child Neurology Society: multiple professional and scientific committee

Awards

  • Kiffin Penry Pediatric Epilepsy award
  • Elected Fellow, American Academy of Pediatrics
  • Judge, Neuroscience Research, Cleveland Clinic
  • Marquis “Who’s Who in America”
  • “Top Physicians of America”, Consumers’ Research Council of America, Washington, DC Best Doctors in America
  • America’s Top Pediatricians, Consumers Research Council of America
  • Cleveland Clinic Caregiver Appreciation Award, Core value: service
  • Fellow, American Epilepsy Society
  • Judge, Research Awards, Association of Child Neurology Meeting, New Delhi, India
  • Top Doctors of America (Castle Connolly)

Professional Memberships

American Epilepsy Society; American Academy of Neurology; Child Neurology Society (USA); American Academy of Pediatrics; International Child Neurology Association

Research & Publications

See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.

As of 2025-11-07, Dr. Gupta has reported the financial relationships with the companies listed below.

Consulting and/or Speaking. Dr. Gupta receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • UCB Pharmaceuticals, Inc.
  • Catalyst Pharmaceuticals
  • Jazz Pharmaceuticals, plc

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Insurances Accepted

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Ratings & Reviews

4.7 out of 5

52 ratings, 5 reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Explains
Courtesy Respect & Concern
Patient Rating of Doctor
    5 out of 5 stars
    Reviewed on 4/6/2026

    Always a great experience with Dr. Gupta!

    5 out of 5 stars
    Reviewed on 11/19/2025

    We felt listened to, taken seriously, and appreciate the time and expertise Dr. Gupta has given our son and family.

    5 out of 5 stars
    Reviewed on 6/26/2025

    Dr Gupta and Staff have been absolutely phenomenal!!

    5 out of 5 stars
    Reviewed on 6/10/2025

    Dr Gupta always takes time to listen and talk with us. He never makes it feel like he is rushing . He explains things and is patient

    5 out of 5 stars
    Reviewed on 5/19/2025

    Dr. Ajay Gupta is thorough doctor and we were fortunate to have him since 2019. Unfortunately, because of our HealthShare Plan and Cleveland Clinic not being able to bill, we have to switch hospitals/doctor. We are thankful for his expertise.