Highlights
Age Groups Seen
- Adult
Languages
- Portuguese
- English
Gender
MaleAbout Andre Machado
Biography
Andre Machado, MD, PhD is the Chairman of the Neurological Institute and the Charles and Christine Carroll Family Endowed Chair in Functional Neurosurgery. Dr. Machado performs deep brain stimulation (DBS) surgery for patients with Parkinson’s disease, tremor, dystonia and obsessive-compulsive disorder as well as surgical procedures for patients with trigeminal neuralgia, intractable pain syndromes and spasticity.
Dr. Machado is a Professor of Neurosurgery at the Cleveland Clinic Lerner College of Medicine and has Joint Appointments in the Departments of Neuroscience and Biomedical Engineering. He is the past Chairman for the Joint Pain Section of the CNS/AANS and Vice-President of the American Society of Stereotactic and Functional Neurosurgery.
Dr. Machado is an Associate Chief of Staff at Cleveland Clinic and leads several enterprise-level projects with the Office of the Chief of Staff, including innovations in the model of care and a new program for professional career development.
Dr. Machado received his medical degree from the University of Sao Paulo in 1997. He completed his residency in the same institution in 2003 and obtained his PhD in 2004. He came to Cleveland Clinic in 2004, completed his fellowship in Stereotactic and Functional Neurosurgery in 2006 and has been on the staff at Cleveland Clinic since then.
Dr. Machado leads several deep brain stimulation and neuromodulation clinical trials as well as laboratory research. His research in deep brain stimulation for thalamic pain syndrome was awarded the National Institutes of Health Director’s New Innovator’s Award. His current research is aimed at developing novel treatments to promote rehabilitation after stroke and other acquired brain injuries and is funded by the NIH BRAIN initiative.
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Education & Board Certifications
Education
- Fellowship: Cleveland Clinic, 2006
- Graduate School: University of Sao Paulo Faculty of Medicine, 2004
- Residency: University of Sao Paulo Hospitals and Clinics, 2004
- Internship: Universidade de Sao Paulo, 1998
- Medical Education: University of Sao Paulo Faculty of Medicine, 1997
Board Certifications
- Neurological Surgery: Brazilian Society of Neurosurgeons, 2004
Awards
Professional Memberships
Innovations & Patents
- Preclinical research on deep-brain stimulation for rehabilitation of motor function following strokes
- First randomized clinical trial of deep brain stimulation for thalmic pain syndrome
- Research in new devices for deep brain stimulation
- Research in new devices for neuromodulation, invasive and non-invasive
- Emerging applications of deep brain stimulation including psychiatric disorders and traumatic brain injury
- Intraluminal electrode assembly. US 7,532,938
- Methods of treating medical conditions by neuromodulation of the cerebellar pathways. US 7,640,063
- Methods of treating neurological conditions by neuromodulation of interhemispheric fibers. US 7,697,991
- Corpus Callosum Neuromodulation Assembly. US 7,725,196
- Method and system for treating acute heart failure by neuromodulation. US 8,818,501
- Methods and systems of achieving hemodynamic control through neuromodulation. 20060100667
- Systems and methods for neuromodulation using pre-recorded waveforms. 20080208284
- Methods and apparatus for securing a neuromodulation lead to nervous system tissue or tissue surrounding the nervous system. 2009007644
- Corpus Callosum Neuromodulation Method. US 8.942,812
Research & Publications
See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)
Industry Relationships
Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.
As of 2026-03-03, Dr. Machado has reported the financial relationships with the companies listed below.
Royalty Payments. Dr. Machado receives or has the right to receive royalty payments for inventions or discoveries commercialized through the companies shown below:
- Ceraxis Health, Inc.
Right to Future Distribution of Cleveland Clinic Financial Interest. Dr. Machado may receive future financial benefits from the Cleveland Clinic for inventions or discoveries commercialized through the companies shown below:
- Ceraxis Health, Inc.
- Enspire DBS
Consulting and/or Speaking. Dr. Machado receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:
- Oaya, Inc.
Equity Dr. Machado owns stock or stock options in the following companies for activities as a founder, inventor, discoverer, developer:
- Ceraxis Health, Inc.
Fiduciary Role. Dr. Machado serves in a fiduciary capacity, such as an elected officer, director or chief medical officer, for the following companies or other entities:
- Enspire DBS
- Ceraxis Health, Inc.
Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.
* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.
Insurances Accepted
Video
Ratings & Reviews
5 out of 5
62 ratings, 3 reviewsThe Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
- 5 out of 5 starsReviewed on 2/27/2026
Had problems trying to get my audio turned on. Somehow It was muted!I apologize for the issue Still don''t fully understand how got it fixed but I truly appreciate the patience displayed by Dr Machado.
- 5 out of 5 starsReviewed on 2/27/2026
Exceptional Dr. / Outstanding Bedside manor!
- 5 out of 5 starsReviewed on 2/20/2026
My visit with Dr Machado was done in person this time