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Cassandra Calabrese

Cassandra Calabrese, DO

Rheumatology

Need help scheduling? Call (216) 445-6996

Highlights

Age Groups Seen

  • Adult

Languages

  • English

Gender

Female

About Cassandra Calabrese

Biography

Cassandra Calabrese completed a combined fellowship in rheumatology and infectious diseases, and holds joint appointments in the rheumatology department and the infectious disease department at the Cleveland Clinic. She specializes in infections in the setting of immunosuppressive treatment for rheumatic diseases, rheumatic manifestations of infectious diseases and human immunodeficiency virus, and has a particular interest in infection prevention and immunizations.

In addition, she specializes in rheumatic immune related adverse events from cancer immunotherapy, and is part of a multidisciplinary referral clinic with the Taussig Cancer Center at the Cleveland Clinic.

Locations

  1. CA Building - Taussig Cancer Center
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  2. Cleveland Clinic Main Campus
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  3. A Building - Crile Building
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  4. A Building - Crile Building
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Education & Board Certifications

Education

  • Fellowship: Cleveland Clinic, 2018
  • Fellowship: Cleveland Clinic, 2017
  • Residency: Cleveland Clinic, 2014
  • Medical Education: Heritage College of Osteopathic Medicine, 2011
  • Undergraduate: Kenyon College, 2007

Board Certifications

  • Infectious Disease: American Board of Internal Medicine, 2018
  • Rheumatology: American Board of Internal Medicine, 2017

Additional Training

  • Rheumatology ABIM board certified
  • Infectious Disease ABIM board certified

Research & Publications

See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.

As of 2026-03-23, Dr. Calabrese has reported the financial relationships with the companies listed below.

Consulting and/or Speaking. Dr. Calabrese receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • OpenEvidence
  • Sanofi S.A.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Insurances Accepted

Review a list of accepted insurance plans for our Northeast Ohio locations or learn more about purchasing a contracted managed care plan.

Video

Ratings & Reviews

5 out of 5

132 ratings, 30 reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Explains
Courtesy Respect & Concern
Patient Rating of Doctor
Search reviews
    5 out of 5 stars
    Reviewed on 3/10/2026

    Dr. Calabrese is amazing! I travel from Erie to see her. She is thorough and doesn''t rush me. She makes sure all of our questions are answered. Cleveland Clinic is lucky to have her!

    5 out of 5 stars
    Reviewed on 3/9/2026

    Dr. Calabrese and her team are caring, kind and very responsive.

    5 out of 5 stars
    Reviewed on 2/12/2026

    Dr. Calabreeze is so thoughtful, and very kind. She is very through! So thankful for her in my treatment of PMR.

    5 out of 5 stars
    Reviewed on 1/28/2026

    Dr Calabrese is an exceptional provider. Truly takes a sincere interest in giving the best care possible. I trust her judgment and her guidance. She was very patient with me and allowed me to ask questions to fully understand our next steps for care. Excellent provider

    5 out of 5 stars
    Reviewed on 1/14/2026

    Dr Calabrese is always prompt in regard to any messages I sent to her.

    5 out of 5 stars
    Reviewed on 1/14/2026

    As, always Dr. Calabrese has provided excellent health care. She has always been concerned and caring, and promptly responds to my messages. My condition has greatly improved due to her (and Dr. Fernandez') efforts.

    5 out of 5 stars
    Reviewed on 1/14/2026

    Dr. Cassandra Calabrese is awesome . Most importantly, she cares, communicates and follow-ups.

    5 out of 5 stars
    Reviewed on 1/8/2026

    Dr. Calabrese cares her patience and helps them understand about their body

    5 out of 5 stars
    Reviewed on 1/8/2026

    Give her a raise. Best rheumatologist I have ever had

    5 out of 5 stars
    Reviewed on 12/16/2025

    Dr Cassandra Calabrese is an exceptional doctor.

    5 out of 5 stars
    Reviewed on 12/16/2025

    During the appointment Dr. C. Asked several times if I had any questions or concerns.

    5 out of 5 stars
    Reviewed on 10/16/2025

    Dr. Calabrese is a very caring physician.

    5 out of 5 stars
    Reviewed on 10/7/2025

    Was very impressed with how Dr Calabrese and Dr Moudgil communicated with my treatment.

    5 out of 5 stars
    Reviewed on 10/7/2025

    Dr Calabrese was so nice and courteous. Really listened to my concerns and explained treatment very clearly.

    5 out of 5 stars
    Reviewed on 9/19/2025

    Dr Calabreeze was just wonderful! She listened to all my concerns and set a plan in motion.

    5 out of 5 stars
    Reviewed on 9/10/2025

    Love my physician

    5 out of 5 stars
    Reviewed on 8/11/2025

    Dr. Calabrese is always open to my opinions/decisions.

    5 out of 5 stars
    Reviewed on 8/11/2025

    Unlike other practices, I always leave Cleveland Clinic knowing I'm in good hands and with hope for the future. Thank you!

    5 out of 5 stars
    Reviewed on 8/11/2025

    Very easy to get an appt., seeing a dr., and very kind.

    5 out of 5 stars
    Reviewed on 8/11/2025

    Excellent doctor in every aspect and interacts with patients professional and courteous. The staff is excellent and respectful.

    5 out of 5 stars
    Reviewed on 7/21/2025

    Cassandra Calabrese bedside manner made me feel comfortable. She listened and proposed next steps immediately. She was great!

    5 out of 5 stars
    Reviewed on 6/18/2025

    I always look forward to my zoom visits with Dr. Cassandra Calabrese. She's very knowledgeable about my health and how we are treating it

    5 out of 5 stars
    Reviewed on 6/18/2025

    Dr. Calabrese always ask if there is anything she can do to help me and makes sure she's listens

    5 out of 5 stars
    Reviewed on 6/16/2025

    Dr. Calabrese has always been a accompassionate, good listener , and knowledgeable physician!

    5 out of 5 stars
    Reviewed on 6/6/2025

    Dr. Calabrese is exceptional.

    5 out of 5 stars
    Reviewed on 6/6/2025

    Dr. Calabrese is very accommodating.

    5 out of 5 stars
    Reviewed on 5/28/2025

    My wife knew her father, Leonard Calabrese, who was excellent. Dr. Casandra Calabrese has an amazing extensive breadth of knowledge and IT shows. We were honored to have her consult with us. Her extensive education and foundation is coupled with her delightful personality. We wish ALL doctors were of her EXCELLENT caliber.

    5 out of 5 stars
    Reviewed on 5/21/2025

    Totally a positive experience with Dr. Calabrese! She is exceptional.

    5 out of 5 stars
    Reviewed on 5/14/2025

    Have not heard from the doctor about diagnosis yet

    5 out of 5 stars
    Reviewed on 5/7/2025

    Dr.Calabrese was upbeat and encouraging. She was professional yet friendly. I have confidence in her opinions and treatment options.