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Francois Bethoux

Francois Bethoux, MD

Physical Medicine and Rehabilitation

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Highlights

Age Groups Seen

  • Adult

Languages

  • French
  • English

Gender

Male

About Francois Bethoux

Title

Chairman, Department of Physical Medicine & Rehabilitation

Biography

Francois Bethoux, MD, serves as the Director of Rehabilitation Services at the Cleveland Clinic Mellen Center. He was born in 1964 in Paris, France. He completed his medical studies and residency in Physical Medicine and Rehabilitation in Lyon, France. After moving to the United States to complete a Neuroimmunology fellowship at the Mellen Center for Multiple Sclerosis Treatment and Research (affiliated with the Cleveland Clinic Foundation), he remained on staff and today serves as the Director of Rehabilitation Services. 

Dr. Bethoux's research interests include outcomes measurements in both general and multiple sclerosis (MS)-specific neurorehabilitation, gait analysis and evaluation of symptomatic therapies and rehabilitative interventions for spasticity in MS and other disorders of the central nervous system.

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Locations

  1. U Building - Mellen Center
    • phone:
    • fax:

Education & Board Certifications

Education

  • Fellowship: Cleveland Clinic, 2000
  • Fellowship: MetroHealth Medical Center, 1995
  • Residency: University Hospitals of Saint Etienne, 1994
  • Graduate School: University of Burgundy, 1994
  • Internship: University Hospitals of Lyon, 1990
  • Medical Education: Alexis Carrel Medical School, 1988

Board Certifications

  • Physical Medicine & Rehabilitation: French Board of Physical Medicine and Rehabilitation, 1994

Awards

  • Principal Investigator, “Efficacy Of  A Hip  Flexion Assist Orthosis In Ambulatory Multiple Sclerosis Patients,” National Multiple Sclerosis Society grant, 2010-2012
  • Principal Investigator, “Randomized, controlled trial of rehabilitation following acute relapses of MS,” study funded by the National Multiple Sclerosis Society, 2000-2003

Professional Memberships

American Academy of Neurology; International Society for Quality of Life Research; French Society of Physical Medicine and Rehabilitation; Rehabilitation in MS Society

Innovations & Patents

  • Participated in the design and testing of a new leg brace (hip flexion assist orthosis) in patients with multiple sclerosis. A pilot study of the brace was funded by the National Multiple Sclerosis Society. The results of the study were accepted for publication in the Archives of Physical Medicine and Rehabilitation. Patients with hip flexor weakness using the brace have experienced significant improvement of walking performance and leg strength.

Research & Publications

See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.

As of 2025-09-21, Dr. Bethoux has reported the financial relationships with the companies listed below.

Royalty Payments. Dr. Bethoux receives or has the right to receive royalty payments for inventions or discoveries commercialized through the companies shown below:

  • Springer
  • Biogen Idec, Inc.
  • Qr8 Health, Inc.

Consulting and/or Speaking. Dr. Bethoux receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • Bristol-Myers Squibb

Right to Future Distribution of Cleveland Clinic Financial Interest. Dr. Bethoux may receive future financial benefits from the Cleveland Clinic for inventions or discoveries commercialized through the companies shown below:

  • Qr8 Health, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Insurances Accepted

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Video

Ratings & Reviews

4.9 out of 5

79 ratings, 17 reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Explains
Courtesy Respect & Concern
Patient Rating of Doctor
Search reviews
    5 out of 5 stars
    Reviewed on 2/19/2026

    Dr Bethoux works very closely with our physical therapist to ensure that we get optimal benefit from our Botox Injections precisely at the optimal dose for each muscle. We are extremely grateful for his wisdom and skill!

    5 out of 5 stars
    Reviewed on 2/11/2026

    My experience in mtg Dr. Bethoux was AMAZING! It was really nice to meet such a kind man, he listened to me, and promised to follow through with another recommendation. I liked the way you can observe sincerity, humbleness, and a true interest abt my health.

    5 out of 5 stars
    Reviewed on 2/11/2026

    Dr Bethoux always listens and advises me on my treatment. Shows me concern for my care and recovery.

    5 out of 5 stars
    Reviewed on 1/8/2026

    I would give Dr. Bethoux straight 10s if available. His compassion and care was outstanding.

    5 out of 5 stars
    Reviewed on 12/24/2025

    I've always had great drs and nurses at Cleveland Clinic. Dr Bethoux is wonderful. Always has been. I'm very happy to come to Cleveland Clinic and often recommend it

    5 out of 5 stars
    Reviewed on 10/22/2025

    Dr was very thorough on my exam.

    5 out of 5 stars
    Reviewed on 7/30/2025

    Dr. Bethoux is outstanding! He demonstrated confident confidence, ethical practices and was focused on me as a patient. His evaluation was thorough and he provided answers and explanations to my questions. He is instrumental in ensuring I trial assistive electronic devices that will aid with my mobility. He has surrounded himself with a great team. It's apparent they demonstrate the utmost respect for each other!! The visit was ANOTHER great experience!!

    5 out of 5 stars
    Reviewed on 7/28/2025

    We love Cleveland Clinic and have had top notch care. Dr listens to us and takes the time figure us out.

    5 out of 5 stars
    Reviewed on 7/18/2025

    Dr. Bethoux has a caring manner, which is much appreciated.

    5 out of 5 stars
    Reviewed on 7/9/2025

    Dr Bethoux always treated my son and I well. Staff and he make him feel comfortable and at ease.

    5 out of 5 stars
    Reviewed on 7/9/2025

    Dr Bethoux is an extraordinarily kind and compassionate doctor who explains the procedure fully.

    5 out of 5 stars
    Reviewed on 6/26/2025

    Dr. Bethoux was very gentle, extremely pleasant and used excellent technique! He is also very attentive and takes great precautions to make the injections as painless as possible. He was also quick and highly efficient? We are extremely grateful for his excellent technique and pleasant personality. He is such a blessing!!

    5 out of 5 stars
    Reviewed on 6/26/2025

    Dr Bethoux and his staff were excellent Very thoughtful, kind concerned - they are just the best

    5 out of 5 stars
    Reviewed on 5/28/2025

    I appreciate having such a knowledgeable, attentive, and empathetic doctor. He is such an asset to Cleveland Clinic!

    5 out of 5 stars
    Reviewed on 5/14/2025

    We appreciate Dr. Francois Bethoux, and his nurse Jackie so very much. They are very helpful and professional at all times. Thank you so much!

    5 out of 5 stars
    Reviewed on 5/14/2025

    There is no one like my Dr Bethoux he's the best

    5 out of 5 stars
    Reviewed on 5/14/2025

    I will definitely recommend Dr Francois Bethoux to someone.