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James Fernandez

James Fernandez, MD, PhD

ImmunologyAllergy and Immunology

Need help scheduling? Call (216) 444-6933

Highlights

Age Groups Seen

  • Adult

Languages

  • English

Gender

Male

Locations

  1. A Building - Crile Building
    • phone:
    • fax:
  2. A Building - Crile Building
    • phone:
    • fax:

Education & Board Certifications

Education

  • Fellowship: Brigham & Women's Hospital, 2012
  • Residency: MetroHealth Medical Center, 2009
  • Medical Education: Case Western Reserve University School of Medicine, 2006
  • Undergraduate: Case Western Reserve University School of Medicine, 2002
  • Undergraduate: Northwestern University, 1994

Professional Memberships

Clinical Immunology Society; American Academy of Allergy, Asthma & Immunology; AmericanנCollege of Allergy, Asthma & Immunology; United States Immunodeficiency Network

Research & Publications

See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.

As of 2026-03-20, Dr. Fernandez has reported the financial relationships with the companies listed below.

Consulting and/or Speaking. Dr. Fernandez receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • Takeda Pharmaceuticals North America, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Insurances Accepted

Review a list of accepted insurance plans for our Northeast Ohio locations or learn more about purchasing a contracted managed care plan.

Ratings & Reviews

5 out of 5

114 ratings, 25 reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Explains
Courtesy Respect & Concern
Patient Rating of Doctor
Search reviews
    5 out of 5 stars
    Reviewed on 4/8/2026

    Dr Fernandez is the BEST!

    5 out of 5 stars
    Reviewed on 4/8/2026

    Dr Fernandez is the BEST! However getting an appointment with him is extremely difficult because he gets so booked out (at least 6-7 months)

    5 out of 5 stars
    Reviewed on 4/6/2026

    Dr Fernandez is an excellent physician. He is well versed in my condition and how to treat it to keep me well.

    5 out of 5 stars
    Reviewed on 4/6/2026

    Doctor is a great person. One of the very best doctor and person I have ever had.

    5 out of 5 stars
    Reviewed on 3/30/2026

    I''m very happy with Dr. Fernandez.

    5 out of 5 stars
    Reviewed on 3/30/2026

    Dr. Fernandez is an exceptional immunologist and a true advocate for his patients. He is incredibly intelligent and highly knowledgeable in his field, and he takes the time to thoughtfully evaluate complex medical issues. What truly sets him apart is his genuine kindness and compassion. He listens carefully, treats his patients with respect, and works diligently to ensure they receive the best possible care. I am very grateful to have a physician who is both clinically brilliant and deeply committed to the well-being of his patients

    5 out of 5 stars
    Reviewed on 3/5/2026

    Dr. Fernandez is one of the best physicians in the Cleveland Clinic system. He always listens, takes his time, and answers all of my questions. He does not hurry me, he is patient and that means a great deal to me since I have had two strokes.

    5 out of 5 stars
    Reviewed on 3/3/2026

    Dr Fernandez puts you at ease with his active listening and feedback.

    5 out of 5 stars
    Reviewed on 1/28/2026

    Dr.Fernandez is wonderful!

    5 out of 5 stars
    Reviewed on 1/9/2026

    Dr.Fernandez is a wonderful doctor and has helped me greatly

    5 out of 5 stars
    Reviewed on 12/24/2025

    Dr. Fernandez is great - always prepared and knows what's happened since I've seen him last. Efficient and friendly - We can chat briefly, go over needs for the upcoming year and are done often even before the official appointment time.

    5 out of 5 stars
    Reviewed on 12/18/2025

    A pleasure to have Dr Fernandez and Cleve ckinic

    5 out of 5 stars
    Reviewed on 11/7/2025

    Dr Fernandez is highly qualified, efficient and saved me a ton of heartaches navigating my complicated health issues

    5 out of 5 stars
    Reviewed on 9/22/2025

    Dr. Fernandez has taken excellent care of my issues with my immune system

    5 out of 5 stars
    Reviewed on 9/10/2025

    Dr Fernandez listens, provides feedback, and answers my questions thoroughly.

    5 out of 5 stars
    Reviewed on 8/27/2025

    The man on first floor at registration kiosk saw Dr. Fernandez was going to be seeing me and said Wow! You have a great doctor. That made me feel really confident about receiving good treatment.

    5 out of 5 stars
    Reviewed on 8/27/2025

    Whole experience was great from the valet to the lab and physician.

    5 out of 5 stars
    Reviewed on 8/20/2025

    It is truly amazing that Dr. Fernandez would show such a level of concern as to immediately respond to his secretary's efforts to help me and be willing to have a telephone appointment with me while he was on vacation! He was very kind and compassionate and said something to the effect that he knew I must have special need to have contacted them as I did--and I was feeling miserable. What an encouragement! Thank you so much to Dr. Fernandez and to Celeste for her help as well.

    5 out of 5 stars
    Reviewed on 8/1/2025

    Dr. Fernandez saved my life. He is thorough, listens to my questions and concerns.

    5 out of 5 stars
    Reviewed on 7/22/2025

    Dr. Fernandez is not only a phenomenal and knowledgeable doctor but he is the most compassionate and empathetic doctor! I am so grateful he's in charge of this piece of my health puzzle. I value and trust his treatment plan!

    5 out of 5 stars
    Reviewed on 6/17/2025

    Difficult to get in person appt w/Dr Fernandez -he's very busy but I'm so grateful he's my dr so it's okay

    5 out of 5 stars
    Reviewed on 6/17/2025

    Excellent Dr - has truly saved my life! And continues to be instrumental in my healthcare as my disease he treats is a chronic rare disease

    5 out of 5 stars
    Reviewed on 5/28/2025

    Dr. Fernandez is a fantastic doctor. He's been my doctor for years and I will be with him till he retires! I'm so thankful!

    5 out of 5 stars
    Reviewed on 5/28/2025

    Dr Fernandez has always listened to my concerns and he is a very caring dr

    5 out of 5 stars
    Reviewed on 5/16/2025

    I recently had some changes with my health condition, and Dr. Fernandez was very helpful in making sure to take this into account in terms of the condition that he is treating me for and to get ahead of any potential issues.