Highlights
Age Groups Seen
- Adult
Languages
- Chinese
- English
Gender
MaleAbout Jianguo Cheng
Biography
Jianguo Cheng, MD, PhD, serves as a Professor of Anesthesiology and the Director of the Cleveland Clinic Multidisciplinary Pain Medicine Fellowship Program. He has a distinguished background, having previously held the position of President of the American Academy of Pain Medicine (AAPM) and Chair of the US Section of the World Institute of Pain. Dr. Cheng played a critical role in the US Department of Health and Human Services (HHS) Pain Management Best Practices Inter-agency Task Force (PMTF), leading the drafting of the Task Force's Report to the U.S. Congress aimed at identifying gaps in pain management and proposing recommendations.
Dr. Cheng serves as a member of the National Academy of Medicine (NAM) Action Collaborative on Combating Substance Use and Opioid Crises, contributing to the development of the 3Cs Framework for Pain and Unhealthy Substance Use: Minimum Core Competencies for Interprofessional Education and Practice. Dr. Cheng also served in the Centers for Medicare & Medicaid Services (CMS) Expert Work Group (EWG), where he participated in the development, specification, and maintenance of clinical quality measures.
Recognized for his clinical expertise, Dr. Cheng has received accolades such as inclusion in Best Doctors in America, Top Doctors in America, and acknowledgment as one of the 70 Best Pain Management Physicians in the US by Becker's ASC Review. In his role as a principal investigator, he has secured research grants exceeding $10 million from prestigious institutions like the National Institutes of Health (NIH) and the Department of Defense, conducting groundbreaking research in areas such as stem cells, opioid tolerance, and chronic pain.
Dr. Cheng's extensive contributions extend to academia, with over 200 research papers, review articles, and book chapters published. His inventions and technology products are globally utilized in clinical practice. He has held positions such as Safety Officer of the Data and Safety Monitoring Board (DSMB) at the National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and served on grant review panels/committees for the NIH and the Department of Defense.
As an educator, Dr. Cheng has published three textbooks and delivered over 200 lectures worldwide. The textbooks include: Fundamentals of Pain Medicine (Springer-Nature, 2018), Neuropathic Pain (Oxford University Press, 2019), and Neuroimmune Interactions: Mechanisms and therapeutics (Springer-Nature, 2023). Dr. Cheng directs one of the largest and most esteemed pain medicine training programs in the US, having trained over 200 clinical fellows and postdoctoral research fellows. Recognized as Best Teacher of the Year and Staff of the Year in Anesthesiology/Pain Medicine at the Cleveland Clinic, his program has been honored with the American Academy of Pain Medicine Pain Medicine Fellowship Excellence Award.
Beyond his institutional roles, Dr. Cheng has actively contributed to organizations such as the Association of University Anesthesiologists (AUA, Scientific Advisory Board), American Board of Anesthesiology (ABA, Board Examination Question Writer), American Society of Anesthesiologists (ASA, multiple committees), and American Academy of Regenerative Medicine (Board of Directors). His editorial roles include serving as Senior Editor, Associate Editor, and Section Editor for scientific journals like "Pain Medicine", "Pain Practice", "Pain Physician", "Frontiers in Pain Research", and "Therapeuticals".
Dr. Cheng's extensive list of awards and honors, totaling more than 80, reflects his significant contributions to the field. His research interests and clinical expertise encompass a wide range, including the mechanisms and therapeutic strategies of chronic pain, sensory-motor integration in the spinal cord, clinical applications of neuromodulation, and stem cell biology and applications in pain medicine.
Dr. Cheng was trained in Pain Medicine at Harvard University (Fellowship at Massachusetts General Hospital), Surgery and Anesthesiology at University of Louisville (Residency), Neurology at the Qingdao University, and Neurosciences at the University of Guelph (PhD, Biophysics), University of Manitoba, and University of Alberta (PDF) in Canada.
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Education & Board Certifications
Education
- Fellowship: Massachusetts General Hospital, 2005
- Residency: University of Louisville Hospital, 2004
- Internship: University of Louisville Hospital, 2002
- Medical Education: University of Guelph, 1995
- Residency: Qingdao Medical College, 1991
- Medical Education: Qingdao Medical College, 1986
Board Certifications
- Pain Medicine: American Board of Anesthesiology, 2008
Professional Highlights
- President of the American Academy of Pain Medicine (2018~-2019)
- Member, US Department of Health and Human Services (HHS) Pain Management Best Practices Inter-agency Task Force (PMTF Feb 21, 2018-2019)
- Member of National Academy of Medicine Action Collaborative on Countering the US Opioid Epidemic, 2018-2022.
- Member of the Centers for Medicare & Medicaid Services (CMS) Expert Work Group (EWG) on the development of the measure evaluating potential opioid overuse. 2016-2021.
- Chairman, USA Section of World Institute of Pain (2013-2015).
- Board of Directors, American Academy of Pain Medicine (AAPM) (2014-2020)
- Board of Directors, American Academy of Regenerative Medicine (AARM) (2016~)
- Academy of Medicine of Cleveland & Northern Ohio (AMCNO), 2019-2021.
- Senior Editor/Section Editor, Pain Medicine (Official Journal of American Academy of Pain Medicine), 2015-present)
- Associate Editor, Pain Practice (Official Journal of World Institute of Pain) (2011-2017)
- Scientific Advisory Board, the Association of University Anesthesiologists (AUA) (2015-2018).
- Board of Directors, American Academy of Pain Medicine (AAPM) (2013-present).
- Chairman, AAPM Scientific Review/Clinical Guideline Committee (2011-present).
- Member of National Institutes of Health Study sections/Grant review committee (National Institutes of Health Special Emphasis Panel/Scientific Review Group.
- Expert Reviewer of grant applications to the US Army Medical Research and Material Command, the Scientific Peer Advisory and Review Services division of the American Institute of Biological Sciences (AIBS).
- Published more than 260 research papers, reviews, book chapters, and abstracts.
- Received research grants of more than $4 million from the National Institutes of Health, the Department of Defense, the Lisa Dean Moseley Foundation, and other funding agencies.
- Executive Board Member, Association of Pain Program Directors (2013-2016).
- Committee Member, American Society of Anesthesiologists (ASA) Committee on Pain Medicine (2013-2017)
- Committee Member, ASA Educational Track Subcommittee on Pain Medicine (2014~).
- Pain Medicine Examination Committee, American Board of Anesthesiology (ABA), the American Board of Physical Medicine and Rehabilitation (ABPMR), and the American Board of Psychiatry and Neurology (ABPN), (2013-2018)
- Examiner, World Institute of Pain, Fellow of Interventional Pain Physicians Board of Examination.
- Previously worked or studied in Harvard University, University of Louisville, University of Alberta, University of Manitoba, University of Guelph, and Qingdao University.
- Trained more than 180 postdoctoral fellows, clinical fellows, and clinical research fellows.
- Received more than 60 honors and awards from institutions, societies, and government agencies.
Additional Training
- Leading in Healthcare Leadership Class, Cleveland Clinic Academy and Board of Governors, Cleveland, Ohio, 08/2009-05/2010. A 10-month course focusing on leadership in healthcare, human resource management, emotional intelligence, finances, marketing, organizational culture and team building.
- Program Director Certification Program, Cleveland Clinic Education Institute, Department of Faculty Development, 09/2011-05/2012. Certification of Distinguished Development Award, September of 2013.
- PhD, biophysics, Interdepartmental Group of Biophysics and Department of Human Biology, University of Guelph, Ontario, Canada, 1991-1995
- Postdoctoral Fellow, electrophysiology of neurons: cell membrane and receptors, Department of Physiology/Spinal Cord Research Centre, University of Manitoba Faculty of Medicine, Winnipeg, Manitoba, Canada, 1995-1996
- Postdoctoral Fellow, neural control of locomotion: neural networks and therapeutic strategies, Division of Neuroscience/Department of Physiology, University of Alberta Faculty of Medicine, Edmonton, Alberta, Canada, 1996-1998
Awards
Innovations & Patents
Dr. Cheng holds several US patents and technology transfers/licensing. He is recipient of the Cleveland Clinic 2012 and 2007 Inventor Awards for his achievements in effectively treating back pain generated from the sacroiliac joint and his innovations of stem cell therapy for chronic pain and opioid tolerance. He is also the inventor of a wheelchair powered by electrical stimulation of paralyzed leg muscles, designed for patients with spinal cord injury and the elderly. Dr. Cheng and his partners in Biomotion Inc. developed and commercialize the WalkAide® technology to treat foot drops due to strokes, multiple sclerosis, and other neurological disorders. WalkAide device has been utilized worldwide since 2008.
Research & Publications
See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)
Industry Relationships
Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.
As of 2025-07-11, Dr. Cheng has reported the financial relationships with the companies listed below.
Royalty Payments. Dr. Cheng receives or has the right to receive royalty payments for inventions or discoveries commercialized through the companies shown below:
- Springer Nature
- Boston Scientific Corporation
Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.
* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.
Insurances Accepted
Video
Ratings & Reviews
4.5 out of 5
96 ratings, 10 reviewsThe Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
- 5 out of 5 starsReviewed on 3/26/2026
Dr. Cheng''s knowledge, caring and expertise are beyond what you would expect from a doctor!
- 5 out of 5 starsReviewed on 2/12/2026
Excellent visit with Dr. Cheng. Procedure scheduled for March, can't wait.
- 5 out of 5 starsReviewed on 2/9/2026
Dr Cheng is a wonderful and caring doctor. He really listens to my problems and addresses them. I don't know what I would do without him.
- 5 out of 5 starsReviewed on 12/2/2025
I have always been delighted with the care received at Pain Management. My Doctor, Dr Cheng, is the best.
- 5 out of 5 starsReviewed on 12/2/2025
Dr Chang was wonderful as was his Fellow.
- 5 out of 5 starsReviewed on 11/7/2025
The doctor thoroughly explained the procedure and answered all myquestions
- 5 out of 5 starsReviewed on 10/16/2025
Charvi Malhotra, MD Was the best resident I've seen with Dr cheng.
- 5 out of 5 starsReviewed on 8/4/2025
Everyone I encountered during my visit was professional, compassionate and concerned. Dr Sampson was extremely knowledgeable and supportive regarding my CRPS dx.
- 5 out of 5 starsReviewed on 7/21/2025
Dr. Cheng, and truly every person at the Pain Clinic is and always has been wonderful to me. With a complex case, many previous clinicians have just dismissed my pain. The doctor who I saw just before Dr. Chen was an amazing listener, provided great feedback and advice, and I feel he truly had every desire to get to the bottom of my maladies; same for Dr. Cheng.I am typically seen at the VA which is 10 minutes from my home.I would HAPPILY drive 6+ hrs round-trip to be regularly seen by Dr. Chen and the staff at the Pain Clinic at Cleveland Clinic if it were feasible. I would just like to say thank you to the doctors, staff, and anyone else who helped make my visit possible.
- 5 out of 5 starsReviewed on 5/28/2025
Dr. Cheng is willing to consider a variety of ways to treat my issue.