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Karen James

Karen James, MD

Heart Failure

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Highlights

Age Groups Seen

  • Adult

Languages

  • English

Gender

Female

About Karen James

Biography

Karen James, MD, is a Staff Cardiologist, and a member of the transplantation team in the Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute at the Cleveland Clinic. She is also Director of the Heart Failure Cardio-Oncology clinic.  She is board-certified as a diplomat in internal medicine, cardiovascular disease and advanced heart failure and transplant medicine. Dr. James has a special interest in cardiac transplantation, left ventricular assist devices, congestive heart failure and heart failure in patients treated for cancer.

Dr. James completed her undergraduate degree at Susquehanna University in Pennsylvania, graduating summa cum laude. She received her medical degree from Hahnemann Medical College in Philadelphia. She did her clinical training in internal medicine at Cleveland Clinic, then fellowships in peripheral vascular disease and cardiology. She was appointed to Cleveland Clinic in 1991.

Dr. James is Associate Professor of Medicine in the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. She is principal investigator or co-investigator in many clinical trials focusing on heart failure therapies, transplant arteriosclerosis and heart failure physiology in LVAD patients, to name but a few of her many research efforts.

She is widely published in leading medical journals such as Circulation, American Heart Journal, American Journal of Cardiology and Transplantation on topics related to her specialty interests. She has written a number of chapters in medical textbooks, among them “Heart Disease arising from Pregnancy” and “Inflammatory Cardiomyopathy."  

She is a reviewer of abstracts for publications that include Circulation Heart Failure, Journal of Heart and Lung Transplantation, Cleveland Clinic Journal of Medicine, Journal of Cardiac Failure and Arthritis and Rheumatism. She has presented the results of her research and clinical experience at national and international conferences and symposia and published numerous abstracts on her specialty interests.

Dr. James is a Fellow of the American College of Cardiology (FACC) and a member of the International Society of Heart Transplantation and of the Clinical Council of the American Heart Association.

Locations

  1. Cleveland Clinic Main Campus
    • phone:
    • fax:
  2. Cleveland Clinic Main Campus
    • phone:
    • fax:

Education & Board Certifications

Education

  • Fellowship: Cleveland Clinic, 1989
  • Residency: Cleveland Clinic, 1985
  • Medical Education: Hahnemann University Medical College, 1982
  • Undergraduate: Susquehanna University, 1978

Board Certifications

  • Advanced Heart Failure and Transplant Cardiology: American Board of Internal Medicine, 2010
  • Cardiovascular Disease: American Board of Internal Medicine, 1989
  • Internal Medicine: American Board of Internal Medicine, 1985

Professional Memberships

Fellow, American College of Cardiology

Research & Publications

See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.

As of 2026-03-10, Dr. James has reported no financial relationship with industry that is applicable to this listing.

In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Insurances Accepted

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Video

Ratings & Reviews

4.8 out of 5

131 ratings, 10 reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

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Courtesy Respect & Concern
Patient Rating of Doctor
Search reviews
    5 out of 5 stars
    Reviewed on 1/9/2026

    Dr James has always been excellant.the concern she shows for me is excellent

    5 out of 5 stars
    Reviewed on 12/26/2025

    High level of confidence & trust in provider. Great care.

    5 out of 5 stars
    Reviewed on 12/26/2025

    I always seem to have a very good experience with Dr. James. There are no problems whatsoever.

    5 out of 5 stars
    Reviewed on 11/13/2025

    I felt all involved were helpful and very knowledgeable. I was in great hands and I believe my Doctor really cared.

    5 out of 5 stars
    Reviewed on 7/15/2025

    The care provider explained every step to me

    5 out of 5 stars
    Reviewed on 6/26/2025

    All good. Dr. James was thourough and professional. As always.

    5 out of 5 stars
    Reviewed on 6/23/2025

    I always enjoy talking to Dr. James. She explains my different medication's and plus she encourages me to improve myself

    5 out of 5 stars
    Reviewed on 6/23/2025

    That your James is very considerate of your opinion and helps. You understand why you're on the medication's. She prescribes instead of just giving them to you. I really enjoy having her as my health failure doctor.

    5 out of 5 stars
    Reviewed on 5/5/2025

    Dr. James was very attentive and answered all our questions.

    5 out of 5 stars
    Reviewed on 4/25/2025

    All was good and good experience seeing the doctor