Leonard Calabrese, DO
Rheumatology
Highlights
Age Groups Seen
- Adult
Languages
- English
Gender
MaleAbout Leonard Calabrese
Biography
Leonard H. Calabrese, DO, heads Cleveland Clinic's Section of Clinical Immunology and manages its Clinical Immunology Clinic. He specializes in diseases of the immune system -- in particular, immunodeficiency diseases, such as human immunodeficiency virus (HIV) and other chronic viral infections, which are the subject of both clinical care and investigation. Dr. Calabrese is also Co-director of the Center for Vasculitis Care and Research and has a particular interest in vascular inflammatory disease of the central nervous system.
A graduate of the Kansas City University of Medicine and Biosciences , Dr. Calabrese performed his internal medicine training at Cleveland Clinic in Ohio, followed by a fellowship in rheumatic and immunologic disease. He has been a staff member in Cleveland Clinic's Department of Rheumatic and Immunologic Diseases since 1980.
Recipient of numerous awards and honors, Dr. Calabrese has received an honorary Doctorate of Humane Letters from the Kansas City University of Medicine and Biosciences, the Phillips Medal of Public Service from the Ohio University College of Osteopathic Medicine, the Bruce Hubbard Stewart Award for humanitarianism and Leonard Tow Humanitarianism in Medicine award from the Arnold P Goldman MD Foundation. He holds the R.J. Fasenmeyer Chair of Clinical Immunology and is the director of the RJ Fasenmyer Center for Clinical Immunology. When he was awarded the Theodore F. Classen, DO Chair in Osteopathic Research and Education in 2008 he became the first dual-chair holder in Cleveland Clinic history.
Dr. Calabrese is a member of many professional societies, including the American Association of Immunology, Clinical Immunology Society and the International AIDS Society and the American Osler Society. He is a fellow of the American College of Rheumatology, American College of Physicians and the American College of Sports Medicine.
Dr. Calabrese has lectured nationally and internationally on the subjects of HIV, immunology and rheumatology and is the author of more than 300 published peer-reviewed articles, book chapters and reviews.
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Education & Board Certifications
Education
- Fellowship: Cleveland Clinic, 1980
- Residency: Cleveland Clinic, 1978
- Internship: Cleveland Clinic, 1976
- Medical Education: Kansas City University of Medicine and Biosciences University of Health Sciences College of Osteopat, 1975
- Undergraduate: John Carroll University, 1971
Professional Highlights
- R.J. Fasenmeyer Chair of Clinical Immunology
- Theodore F. Classen, DO Chair in Osteopathic Research and Education
Awards
- Honorary Doctorate of Humane Letters, Kansas City University of Medicine and Biosciences
- Bruce Hubbard Stewart Award for humanitarianism
- Phillips Medal of Public Service, Ohio University
Professional Memberships
Research & Publications
See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)
Industry Relationships
Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.
As of 2026-03-18, Dr. Calabrese has reported the financial relationships with the companies listed below.
Consulting and/or Speaking. Dr. Calabrese receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:
- AstraZeneca
- AbbVie, Inc.
- Amgen, Inc.
- Johnson & Johnson
- Bristol-Myers Squibb
- UCB Pharmaceuticals, Inc.
- Sanofi Genzyme
Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.
* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.