Highlights
Age Groups Seen
- Adolescent
- Adult
Languages
- English
Gender
FemaleLocations
- Twinsburg Family Health and Surgery Center
- 8701 Darrow Road, Twinsburg, OH 44087
- Get Directions
Education & Board Certifications
Education
- Graduate School: Ohio University, 2020
- Undergraduate: Cleveland State Univeristy, 2016
Board Certifications
- Family Nurse Practitioner: American Academy of Nurse Practitioners Certification Board, 2020
Research & Publications
See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)
Industry Relationships
Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.
As of 2025-10-10, Dr. Gruca has reported no financial relationship with industry that is applicable to this listing.
In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.
Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.
* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.
Insurances Accepted
Video
Ratings & Reviews
4.9 out of 5
191 ratings, 29 reviewsThe Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
- 5 out of 5 starsReviewed on 4/6/2026
Melissa Gruca is an OUTSTANDING provider. She is extremely knowledgeable about all the endocrinology issues I have. I have hypothyroidism, insulin resistance, high cholesterol, etc. She has helped me a lot with weight management and in making sure my overall health is good. For example, we talk about vitamin D and B deficiencies and ways to ameliorate ~ even though these are beyond the scope of endocrinology (I think).
- 5 out of 5 starsReviewed on 4/6/2026
Both Dr. Mulligan and Melissa Gruca are VERY busy and usually full for about 6 months.
- 5 out of 5 starsReviewed on 3/9/2026
Melissa is a fantastic care provider
- 5 out of 5 starsReviewed on 1/26/2026
Always a pleasure to see Melissa, she is kind and attentive, answers all of my questions
- 5 out of 5 starsReviewed on 1/26/2026
I absolutely love Melissa. She listens and explains everything. Very caring.
- 5 out of 5 starsReviewed on 1/9/2026
Her plan of care totally aligned with what I had already in my mind.
- 5 out of 5 starsReviewed on 1/9/2026
Melissa is a pleasure to work with. She is very caring, attentive, and exhibits outstanding professionalism.
- 5 out of 5 starsReviewed on 12/8/2025
Melissa is wonderful! She listens to me, discusses my medication and helps me plan ahead. I'm happy to be in her care!!
- 5 out of 5 starsReviewed on 12/8/2025
Melissa GRUCA, CNP is fantastic! She's well-informed, knowledgeable, professional, friendly. Actually, she is my favorite care provider, despite the fact that I am pleased with all of my other CCF care providers. She's the BEST!
- 5 out of 5 starsReviewed on 11/4/2025
Melissa Gruca has been a very caring and knowledgeable person in my life! She explains everything thoroughly and is very instrumental in keeping me healthy!!
- 5 out of 5 starsReviewed on 10/22/2025
First visit with this provider. She was personable, kind, caring and did not rush through the visit
- 5 out of 5 starsReviewed on 10/16/2025
Melissa and Dr. Mulligan have treated me with respect and listen to my concerns with care.
- 5 out of 5 starsReviewed on 10/16/2025
Melissa Gruca is an excellent practitioner. Our session addressed medical and other concerns that I had. She is a great clinician and educator.
- 5 out of 5 starsReviewed on 9/24/2025
She listened and came up with a great plan and one where I felt like I was heard and she was really trying to help. Thank you so much.
- 5 out of 5 starsReviewed on 9/22/2025
Excellent, intelligent & empathic provider.
- 5 out of 5 starsReviewed on 9/11/2025
Melissa was attentive, thoughtful, kind and professional. She carefully reviewed My Chart and asked several questions about it. I found her to be one of the best practitioners I've ever had at CCF
- 5 out of 5 starsReviewed on 9/8/2025
I was very pleased with Melissa Grucca.She is very knowledgeable, kind, respectful. I always feel relaxed after my appts with her
- 5 out of 5 starsReviewed on 7/14/2025
I've already recommended her to several people.
- 5 out of 5 starsReviewed on 7/14/2025
Excellent communicator and listener. She really helped me.
- 5 out of 5 starsReviewed on 6/26/2025
She is exceptional. Genuinely cares, answers concerns, is very knowledgeable, shows concern and compassion. I never feel rushed, and makes sure all my concerns are addressed and always is prompt to reply to my questions between appointments.
- 5 out of 5 starsReviewed on 6/23/2025
Melissa is excellent at what she does; she explained test results thoroughly and offered suggestions to lower my A1C.
- 5 out of 5 starsReviewed on 6/17/2025
She is always very helpful with any questions or concerns I have. Very knowledgeable and interested in my health and condition
- 5 out of 5 starsReviewed on 6/17/2025
Melissa is GREAT! Knowledgeable, professional, yet friendly and personable. Her follow-through is top notch and I feel that she has a sincere Interest in me and my well being.
- 5 out of 5 starsReviewed on 6/9/2025
She is a wonderful provider
- 5 out of 5 starsReviewed on 5/29/2025
Melissa Gruca is the best! It really feels like she works for me. She listened to my challenges and pain points, and worked with me to find solutions that were practical and pragmatic. She is outstanding, and I am grateful for her excellent care!
- 5 out of 5 starsReviewed on 5/22/2025
Answered all my questions and took her time with me.
- 5 out of 5 starsReviewed on 5/4/2025
She was so nice!!!
- 5 out of 5 starsReviewed on 5/4/2025
I wish every doctor I see could be like Melissa! She is so knowledgable and she takes the time to explain not only my illnesses but the treatment approach. Her bedside manner is absolutely the BEST, and her communication beyond the appointment is unmatched! Give that woman a raise!
- 5 out of 5 starsReviewed on 4/28/2025
She explained everything so detailed which I liked and really made me feel like I was talking to a friend