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Sean Lyden

Sean Lyden, MD

Vascular Surgery

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Highlights

Age Groups Seen

  • Adult

Languages

  • English

Gender

Male

About Sean Lyden

Biography

Sean Lyden, MD, is the Chairman of the Department of Vascular Surgery at Cleveland Clinic’s Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute.  He serves as chief medical officer of Excelerate Strategic Health Sourcing, a venture between Cleveland Clinic and Vizient to save health care organizations money with a provider-led, physician-engaged sourcing. 

Specialty Interests: Aortic aneurysm treatment including failed endovascular aneurysm repair, evolving therapies to prevent restenosis in arterial disease, popliteal artery entrapment syndrome, carotid artery disease

Number of Procedures Performed: Dr. Lyden performs more than 200 procedures each year. 

Success Rates: Cleveland Clinic’s Vascular Surgeons are national and international leaders in treating patients with even the most complicated cases, using the most advanced techniques. Much of our experience is in re-operative surgery for patients whose original operations were performed elsewhere, and the department serves as a major referral center for these and other difficult cases throughout Ohio and the surrounding states. We have one of the largest post-graduate training programs in vascular surgery in the United States, and our academic work has been published in scientific journals throughout the world. Success rates for specific procedures are available at http://my.clevelandclinic.org/heart/about-heart-vascular-institute/treatment-outcomes.aspx 

Education and Training: A native of Youngstown, Ohio, Dr. Lyden earned his medical degree from the University of Cincinnati College of Medicine following an undergraduate degree from the University of Notre Dame. He served a residency in general surgery at the University of Tennessee Health Sciences Center in Memphis where he was inducted into the Alpha Omega Alpha Medical Honor Society. His training included a year doing trauma research. He subsequently served a fellowship in vascular surgery at the University of Rochester-Strong Memorial Hospital, Rochester, NY. 

Dr. Lyden was appointed to the Cleveland Clinic staff in 2001. He is Professor of Surgery in the Division of Vascular Surgery at Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. 

Publications and Research: He currently is the Principal Investigator for several international clinical trials and participates in trials studying various topics including thoracic, thoracoabdominal and abdominal stent grafting; lower extremity interventional therapies with drug coated balloons, drug-eluting stents and intravascular lithoplasty; carotid stenting; thrombectomy; and deep venous thrombosis treatments.  Dr. Lyden has given more than 400 presentations of clinical findings at national and international medical symposia and conferences. 

He serves as reviewer for several journals, including the Journal of Vascular Surgery, Annals of Vascular Surgery and the Journal of the American College of Surgeons. He has authored and co-authored more than 175 articles in leading publications, including the Journal of Vascular Surgery, New England Journal of Medicine and Circulation. He also has also authored chapters in several vascular textbooks. 

About Dr. Lyden: “I enjoy my specialty because I end up taking care of a patient for the rest of their lives and I establish close relationships with them and consider them lifetime friends.” 

Leisure Activities: Dr. Lyden enjoys spending time with family, golfing and attending University of Notre Dame football games. 

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Locations

  1. Cleveland Clinic Main Campus
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Education & Board Certifications

Education

  • Fellowship: University of Rochester-Strong Memorial Hospital, 2001
  • Residency: University of Tennessee Health Sciences Center, 1999
  • Medical Education: University of Cincinnati College of Medicine, 1993
  • Undergraduate: University of Notre Dame, 1989

Board Certifications

  • Registered Physician in Vascular Interpretation: Alliance for Physician Certification and Advancement, 2009
  • Vascular Surgery: American Board of Surgery, 2002

Awards

Best Doctors, Cleveland Magazine, 2014

Professional Memberships

American College of Surgeons, Fellow; Society for Vascular Surgery, Distinguished Fellow; Peripheral Vascular Surgery Society; Society for Clinical Vascular Surgery; Midwestern Vascular Surgery Society; International Society for Vascular Surgery; International Society for Endovascular Specialists

Research & Publications

See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.

As of 2026-03-25, Dr. Lyden has reported the financial relationships with the companies listed below.

Consulting and/or Speaking. Dr. Lyden receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • Boston Scientific Corporation
  • Medtronic plc
  • Cook Medical
  • Surmodics, Inc.
  • Contego Medical, Inc.
  • Abbott Laboratories
  • Nectero Therapeutics, Inc.
  • VIVA Physicians
  • Endologix

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Insurances Accepted

Review a list of accepted insurance plans for our Northeast Ohio locations or learn more about purchasing a contracted managed care plan.

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Ratings & Reviews

4.8 out of 5

237 ratings, 37 reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Listens
Explains
Courtesy Respect & Concern
Patient Rating of Doctor
Search reviews
    5 out of 5 stars
    Reviewed on 4/13/2026

    Dr. Lyden was very professional and thorough. As a CRNA he was very patient with my litany of questions!

    5 out of 5 stars
    Reviewed on 4/13/2026

    I would highly recommend Dr. Lyden for surgery!

    5 out of 5 stars
    Reviewed on 4/6/2026

    Dr. Sean Lyden is outstanding in every way. He is an elite Doctor and his bedside manner is second to none.

    5 out of 5 stars
    Reviewed on 4/6/2026

    I appreciated the time the Doctor spent with me!!

    5 out of 5 stars
    Reviewed on 3/16/2026

    Dr. Lyden was helpful in communicating what was next. Keep my spirits up. Nurse Tony was a super nice guy.

    5 out of 5 stars
    Reviewed on 3/16/2026

    Dr. Lyden was very thorough in his examination of my physical condition and in his review of my circulatory test results.

    5 out of 5 stars
    Reviewed on 3/6/2026

    Dr. Sean Lyden was my surgeon and I feel he was extremely attentive to my needs, I was impressed with his expertise and efficiency, his entire staff was awesome, as well as the entire Cleveland Clinic experience.

    5 out of 5 stars
    Reviewed on 2/27/2026

    Dr. Lyden is a very knowledgeable physician he has great bed side mannerism, he makes sure to make sure that you are aware of what is happening in your circumstances.

    5 out of 5 stars
    Reviewed on 2/27/2026

    Nothing but good timeliness and professionalism and knowledge. Dr lyden is a very good doctor.

    5 out of 5 stars
    Reviewed on 2/20/2026

    excellent doctor would recommend

    5 out of 5 stars
    Reviewed on 2/6/2026

    Excellent provider(Dr. Lyden) and staff!

    5 out of 5 stars
    Reviewed on 2/6/2026

    Great confidence in the Doctor.

    2 out of 5 stars
    Reviewed on 1/29/2026

    Dr. Lyden doesn't focus on my aneurism he focuses on my lung cancer. And strongly gives the impression that I'm wasting his time. Very rude Dr. This is the second time this has happened. Last time was infront of other Dr.'s they said Oh that was horrible I can't believe it.

    5 out of 5 stars
    Reviewed on 10/8/2025

    Dr Lyden is a superb surgeon and is the best surgeon that I have seen in my 33 years as a Medevac Commander.

    5 out of 5 stars
    Reviewed on 10/8/2025

    Dr Lyden is a fantastic Dr and and surgeon.

    5 out of 5 stars
    Reviewed on 10/8/2025

    Excellent visitDr Lyden thoroughly explained my condition and answered all our questions

    5 out of 5 stars
    Reviewed on 10/8/2025

    This appointment was an annual follow. The doctor's office schedule the appointment for me. I received notification in ample time to adjust the date/time if needed.

    5 out of 5 stars
    Reviewed on 10/8/2025

    Dr Lyden is the best. He is the reason I travel from Florida to the Clinic.

    5 out of 5 stars
    Reviewed on 10/8/2025

    Dr. Lydon an his staff were a great team. I would recommend him to anyone.

    5 out of 5 stars
    Reviewed on 10/8/2025

    Love Dr Lyden and his nurse Jackie is very good along with his staff

    5 out of 5 stars
    Reviewed on 9/10/2025

    Dr Lyden is very proficient and knowledgeable. He listens and explains things in a way that is easy to understand

    5 out of 5 stars
    Reviewed on 9/10/2025

    Dr Sean is the best!

    5 out of 5 stars
    Reviewed on 8/19/2025

    Dr. Lyden and staff are always there when I need them, explains everything I need to know. Im forever grateful and will continue to be.

    5 out of 5 stars
    Reviewed on 8/4/2025

    Great experience, if you have to go to a doctor that is

    5 out of 5 stars
    Reviewed on 8/4/2025

    Dr lyden was very kind and caring. He made me feel special

    5 out of 5 stars
    Reviewed on 8/4/2025

    My visit with Dr. Lyden was exceptional! He described my health issue in detail and provided a plan going forward. I was very, very impressed with Cleveland Clinic and would highly recommend to others.

    5 out of 5 stars
    Reviewed on 7/29/2025

    Dr. Leyden is the best. I've been seeing him for over17 years. He always has time for my questions no matter what they are.

    5 out of 5 stars
    Reviewed on 7/29/2025

    Dr. Leyden has a wonderful team.

    5 out of 5 stars
    Reviewed on 7/29/2025

    Dr Lyden was the best. Very informative. Explained everything. Promptly contacted my husband when the procedure was done. Very caring and supportive.

    5 out of 5 stars
    Reviewed on 7/22/2025

    Great Dr., confident and straight to the point. That's what we needed in this situation.

    5 out of 5 stars
    Reviewed on 7/15/2025

    Dr. Sean Liden has been amazing as well as his team for all the years I been with them.

    5 out of 5 stars
    Reviewed on 6/10/2025

    I happily travel a long distance to maintain my relationship with Dr. Lyden and his staff. The procedures on my legs has gifted me so much extended ability to enjoy a very physically active (mountain climbing, weightlifting, travel) life without pain and I guess you might say with legs that I am eternally grateful.

    5 out of 5 stars
    Reviewed on 5/29/2025

    I have recommended CCF and Dr. Lyden to friends needing high level medical need.

    5 out of 5 stars
    Reviewed on 5/22/2025

    Have been seeing Dr. Lyden for years. He is absolutely the best.

    5 out of 5 stars
    Reviewed on 5/22/2025

    Dr. Lyden was a very informative and caring doctor . We were happy to have our appointment with him.

    5 out of 5 stars
    Reviewed on 5/12/2025

    Dr Lyden was fabulous! So kind and caring!

    5 out of 5 stars
    Reviewed on 4/25/2025

    Dr.Lyden is the commensurate professional who not only has concern about your medical condition , but also has concern and interest in you as a person and in how your life is going . I'm very thankful the Lord arranged for him to be my surgeon !