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Stanley Hazen

Stanley Hazen, MD, PhD

4.944 ratings, 8 reviews

Preventive Cardiology

Need help scheduling? Call (216) 444-9353

Highlights

Age Groups Seen

  • Adult

Languages

  • English

Gender

Male

About Stanley Hazen

Biography

Stanley Hazen, MD, PhD, received clinical training in Internal Medicine and subspecialty training in Diabetes, Endocrinology and Metabolism from Barnes/Jewish Hospital, St. Louis, MO, and a PhD in Biophysical Chemistry and Molecular Biology from Washington University School of Medicine, St. Louis, MO. He holds multiple leadership positions at the Cleveland Clinic including chair, Department of Cardiovascular & Metabolic Sciences, Lerner Research Institute, co-Section head, Preventive Cardiology & Rehabilitation, Heart, Vascular & Thoracic Institute, and Director, Center for Microbiome & Human Health. Dr. Hazen sees patients within the Preventive Cardiology Clinic, specializing in preventive cardiovascular medicine care of patients including treatment of hyperlipidemia, hypertension, obesity and diabetes. He also sees patients within the Cardiovascular Rehabilitation program. His research interests include studies of mechanisms for the development of cardiovascular disease, with emphasis on understanding the role of the gut microbiome, inflammation and oxidant stress in the pathogenesis of atherosclerosis and other inflammatory diseases.

A renowned physician scientist, Dr. Hazen has made pioneering discoveries in new understandings of mechanisms contributing to cardiovascular and inflammatory disease research. He is credited with numerous seminal discoveries linking gut microbial pathways to cardiovascular disease pathogenesis, as well as enumerating the role of myeloperoxidase and other inflammatory and oxidative pathways in cardiovascular disease. Dr. Hazen is among the top 0.1% cited researchers in the world with over 140,000 citations. He has published over 475 peer-reviewed articles in top tier basic and clinical journals alike in the fields of atherosclerosis, lipoprotein metabolism, gut microbiome, inflammation, vascular biology, and other topics related to preventive cardiovascular medicine. His research in multiple areas has impacted clinical practice, and lays the foundation for FDA- and EU-cleared diagnostic tests for cardiovascular disease risk assessment in use worldwide. He is listed as inventor on over 100 patents, and his research has helped to spawn pharmaceutical development of cardiovascular disease drugs in clinical trials.

Dr. Hazen has received numerous awards including being the Inaugural recipient of the Top 10 Clinical Discovery of the Year (2011) Award, Clinical Research Forum; the American Heart Association/American Stroke Association “top 10 advance in heart disease and stroke science” award (2013); and the American Heart Association Distinguished Scientist Award (2017). Dr Hazen has been honored with election of membership into honorary societies in both science and clinical arenas alike, including the American Society for Clinical Investigation (ASCI) and the American Association of Physicians (AAP). Dr. Hazen is an elected fellow of the American Association for the Advancement of Science (AAAS). Dr. Hazen also is an elected member of the National Academy of Medicine, USA.

Locations

  1. Cleveland Clinic Main Campus
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Education & Board Certifications

Education

  • Fellowship: Barnes-Jewish Hospital, 1996
  • Residency: Barnes-Jewish Hospital, 1994
  • Medical Education: Washington University School of Medicine, 1992
  • Medical Education: Washington University, 1992
  • Undergraduate: Washington University, 1985

Professional Highlights

  • Chair, Gordon Research Conference on Oxygen Radicals
  • Jeffrey M Hoeg Arteriosclerosis, Thrombosis and Vascular Biology Award for Basic Science and Clinical Research
  • Election, Association of American Physicians (AAP)
  • Election, Fellow of American Heart Association Scientific Council for Arteriosclerosis
  • Election, American Society for Clinical Investigation

Awards

  • Howard Hughes Medical Institute Research Fellowship for Physicians Award, 1995-1997 
  • AAP, ASCI, and AFMR Certificate of Achievement Award, 1997 
  • Marilyn Hansen American Thoracic Society Award, 1997
  • Junior Faculty Award, American Federation of Medical Research, 1999 
  • Gill Heart Institute Physician Scientist Award, University of Kentucky, Lexington Ky., 2001 
  • Election, American Society for Clinical Investigation, 2003 
  • John J. Ferchill Award for Innovation, Cleveland Clinic, 2004 
  • Nomination, Howard Hughes Medical Institute Investigator Award, 2004 
  • Vice-Chair, Gordon Research Conference on Oxygen Radicals, 2006 
  •  Jeffrey M Hoeg Arteriosclerosis, Thrombosis and Vascular, 2007 

Professional Memberships

American Society for Clinical Investigation; American Association for the Advancement of Science; American Heart Association Scientific Council for Arteriosclerosis; American Society for Investigative Pathology; American College of Cardiology

Innovations & Patents

  • Patent Title: Diagnostic Methods for Asthma; U.S. Serial Number 09/253,380
  • Patent Title: Myeloperoxidase, a Risk Indicator for Cardiovascular Disease; U.S., Serial Number 10/039,753
  • Patent Title: Treating Inflammation and Associated Complications; Patent Reference Number 09531-030P01 (Pending)
  • Patent Title: Methods of Identifying Subjects at Increased Risk for Cardiovascular Disease; U.S. Serial Number 60/259,340 (Pending)
  • Patent Title: Monitoring Anti-inflammatory and Anti-oxidant Actions of Therapies; U.S. Serial Number (Pending)
  • Patent Title: Diagnostic Method for Identifying Subjects at Risk for Atherosclerosis and its Complications; U.S. Serial Number (Pending)

Research & Publications

See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.

As of 2025-01-08, Dr. Hazen has reported the financial relationships with the companies listed below.

Royalty Payments. Dr. Hazen receives or has the right to receive royalty payments for inventions or discoveries commercialized through the companies shown below:

  • Zehna Therapeutics, LLC
  • Cleveland HeartLab, Inc. (a wholly-owned subsidiary of Quest Diagnostics, Incorporated)
  • Procter & Gamble

Consulting and/or Speaking. Dr. Hazen receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • Zehna Therapeutics, LLC

Right to Future Distribution of Cleveland Clinic Financial Interest. Dr. Hazen may receive future financial benefits from the Cleveland Clinic for inventions or discoveries commercialized through the companies shown below:

  • Zehna Therapeutics, LLC

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Insurances Accepted

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Ratings & Reviews

4.9 out of 5

44 ratings, 8 reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

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Patient Rating of Doctor
Search reviews
    5 out of 5 stars
    Reviewed on 3/5/2026

    Dr. Hazen is a popular doctor. Worth the wait to get an appointment.

    5 out of 5 stars
    Reviewed on 3/5/2026

    Terrific doctor. One of my favorites.

    5 out of 5 stars
    Reviewed on 11/20/2025

    Dr. Hazen was very thorough and clearly had reviewed the package of information I had sent him prior to the appointment. Sharp doctor who is clearly knowledgeable about preventative cardiology. He also communicates well.

    5 out of 5 stars
    Reviewed on 7/22/2025

    Excellent doctor and person. I am very fortunate and appreciative to be in his care.

    5 out of 5 stars
    Reviewed on 5/22/2025

    Dr Hazen is amazing. He answered all my questions, recommended a course of treatment I understand to follow and explained topics in an easy to understand manner.

    5 out of 5 stars
    Reviewed on 5/5/2025

    I would recommend Dr. Hazen to everyone.

    5 out of 5 stars
    Reviewed on 5/5/2025

    Dr. Hazen is a kind and understanding Dr. He takes very long good care of me.

    5 out of 5 stars
    Reviewed on 4/25/2025

    Dr. Hazan was extremely informative and very patient. He spent 2 hours with me going over every detail of my cardiac health. It was refreshing to witness his brilliance and his in-depth knowledge. I feel very lucky and grateful to be his patient.