Stefan Holubar, MD
Inflammatory Bowel Disease SurgeryColon and Rectal Surgery
Highlights
Age Groups Seen
- Adult
Languages
- German
- Swedish
- English
Gender
MaleAbout Stefan Holubar
Title
IBD Surgery Section; Director of Research
Biography
Stefan David Holubar, MD, MS, FACS, FASCRS is a member of the of the Inflammatory Bowel Disease Section and is the Director of Research for the Department of Colon & Rectal Surgery at the Digestive Disease & Surgery Institute. He is also the National Surgical Quality Improvement Surgeon Champion for the Cleveland Clinic Foundation. His appointment as a Professor of Surgery at Cleveland Clinic Lerner College of Medicine is pending.
Background: Dr. Stefan Holubar was born and raised on Long Island. Stefan is a first generation American as his mother immigrated to New York from Stockholm Sweden, and his father family was of Ukrainian descent; Stefan has working knowledge of Swedish and German languages. Stefan’s wife is also a first generation (German)-American and is fluent in French. During medical school Stefan overcame stage 3 colon cancer related to long-standing ulcerative colitis treated with a modified 2-stage IPAA (J-pouch).
Specialty/Clinical Interests: Inflammatory Bowel Disease (IBD), Crohn’s disease, ulcerative colitis, ileoanal pouches including primary pouches, pouch salvage (pouch revision/redo pouch), complex/redo/re-operative colorectal surgery, advanced laparoscopy, robotics, and 2nd opinions including virtually.
Number of Procedures Performed: In addition to seeing hundreds of patients in clinic and virtually, each year, Dr. Holubar performs >250 major colorectal operations annually, most commonly for IBD.
Education and Training: Dr. Holubar received his Medical Degree from the University of Vermont College of Medicine in Burlington VT in 2002. After medical school, he completed his residency at North Shore Long Island Jewish Health System, where he served as Chief Resident in 2007. He continued his clinical training with a clinical fellowship in Colon & Rectal Surgery from Mayo Clinic, Rochester MN where he also completed a 2-year special fellowship during which he earned a Master of Science degree in Clinical & Translational Science, with a focus on Biostatistics and Epidemiology from Mayo Clinic in 2010. During these three years, he published over 30 peer reviewed manuscripts and dozens of national scientific presentations. Throughout his academic training, Dr. Holubar was honored for academic excellence has received several teaching awards. After Mayo, he joined Dartmouth-Hitchcock Medical Center and was eventually appointed Chief of the Division of Colon & Rectal Surgery.
Research, Publications and Speaking:
Presently within the Department of Colon & Rectal Surgery he serves as the IBD Surgery Section Chief, the Director of Research, and as the NSQIP Surgeon Champion for the Cleveland Clinic Foundation, and developed the database structure and oversees the Digestive Diseases Surgery Institute Quality Collaborative (DDSI-QC) for Colorectal Surgery across the Cleveland Clinics. On a national level, Dr. Holubar is actively engaged in helping lead the NSQIP IBD Collaborative, serves as Vice-Chair for the American Society of Colon & Rectal Surgery (ASCRS) IBD Committee, Co-Chair for the Crohn’s & Colitis Foundation’s Professional Education Committee, and is on the Program Committee for the annual scientific meetings for ASCRS, Digestive Diseases Week (DDW), the Crohn’s & Colitis Congress (CCC), and is a regular speak at Advanced in IBD. He also is an active contributing member of the European Crohn’s & Colitis Organization (ECCO). He has lectured nationally and internationally on various IBD topics related to his specialty interests.
He has served as a reviewer for multiple journals, including JAMA Surgery, American Journal of Gastroenterology, Inflammatory Bowel Diseases (Editorial Board member), Journal of Surgical Research, IBD 360, and many others. To date, Dr. Holubar has published over 200 peer-reviewed articles, more of which are on IBD, more than a dozen book chapters, & 1 book (coeditor).
His main clinical and research focus is IBD, with a special interest in all any Med-Surg pouch (IPAA) topics/issues, complex Crohn’s & Colitis, venous thromboembolism prophylaxis in IBD and recently received a grant from the Crohn’s & Colitis Foundation to examine the role of aspirin in VTE prophylaxis. Finally, Dr. Holubar is the PI for the newly funded Crohn’s & Colitis Foundation’s Surgical Cohort and Collaborative, IBD-SIRCQ (Surgical Innovation, Research, & Quality Collaborative).
About Dr. Holubar: “I would describe myself as an honest, flexible and empathic physician-scientist whose principal desire is to relieve human suffering and is why I always am striving to achieve mastery of colorectal surgical techniques. Similarly, my intellectual curiosity, which stems from a childhood appreciation of science-fiction when I was ill from colitis, drives both my approach to clinical decision-making, and desire to advance the state of the art of health care for our patients via perpetual clinical research. It’s an honor to serve my fellow patients and humanity in this manner, and to serve as a role-model for the next generation of healthcare providers.”
Leisure time activities: Enjoys international travel, downhill skiing, boating, surfing, and – all with his wife and three children.
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Education & Board Certifications
Education
- Fellowship: Mayo Clinic, Rochester, Minnesota, 2010
- Graduate School: Mayo Clinic, 2009
- Residency: North Shore Long Island Jewish Health System, 2007
- Medical Education: University of Vermont College of Medicine, 2002
Board Certifications
- Colon and Rectal Surgery: American Board of Colon and Rectal Surgery, 2011
- General Surgery: American Board of Surgery, 2009
Additional Training
Awards
- Research Awards 2022 Best Advanced in Inflammatory Bowel Disease (AIBD) Clinical Abstract Award. Obi Megan et al. Venous Thromboembolism Risk in Hospitalized Tofacitinib-Exposed Patients: A Real-World Experience of 533 Patient
- 2022 Best Advanced in Inflammatory Bowel Disease (AIBD) Surgical Abstract Award. Lincango E, et al. Transanal Ileal Pouch-anal Anastomosis for Inflammatory Bowel Disease (ta-IPAA): A Systematic Review and Meta-analysis
- 2022 American Society of Colon & Rectal Surgeons (ASCRS), Michigan Society of Colon and Rectal Surgeons Award. Holubar, SD et al. Biologics Before Surgery are Not Associated with Infectious Complications After Surgery for IBD
- 2022 Crohn’s & Colitis Congress Poster of Distinction Award: Holubar SD, et al. Current Venous Thromboembolism Chemoprophylaxis Practices After Surgery for IBD: Saves-IBD Trial Initial Report
- 2021 Digestive Diseases Week (DDW)/Society for Surgery of the Alimentary Tract (SSAT) Abstract of the Year Award: Choi S, et al. Is Ileoanal Pouch Excision A Destination Therapy for Inflammatory Bowel Disease? Data From a Quaternary Pouch Referral Center
- 2006 Ira Teischer MD Memorial Award for Excellence in Surgical Education, North Shore-Long Island Jewish (NSLIJ) Health System
- 2006 Excellence in Medical Writing, 3rd prize, North Shore-Long Island Jewish (NSLIJ) Health System Academic Competition
Professional Memberships
Innovations & Patents
- First physician to describe twisted pouch syndrome (TPS), 2019
- First physician to describe the mesenteric excision and exclusion (MEE) procedure for ileocolic Crohn’s disease, 2020
- Created the worlds first 3D virtual J-pouch models, 2021
- Principle investigator for the 1st prospective longitudinal IBD multicenter surgical cohort in the United States, 2022
- Printed the worlds first 3D printed J-pouch models, 2023
Research & Publications
See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)
Industry Relationships
Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.
As of 2025-08-14, Dr. Holubar has reported the financial relationships with the companies listed below.
Donation of Financial Interest. Dr. Holubar has consulted for, received compensation for serving as a fiduciary from, or received royalties from the following companies but instructed them to donate all compensation to not-for-profit causes or to the Cleveland Clinic to support research and education:
- Takeda Pharmaceuticals North America, Inc.
Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.
* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.
Insurances Accepted
Video
Ratings & Reviews
4.8 out of 5
201 ratings, 24 reviewsThe Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
- 5 out of 5 starsReviewed on 4/6/2026
Dr Holubar is amazing. I''m 46 and seen so many GI doctors in my lifetime and Dr Holubar is by far the best one. He is not a medication pusher, he actually listens to me and makes you so comfortable talking about very embarrassing things.
- 5 out of 5 starsReviewed on 3/31/2026
Dr. Holubar is always thorough as well as compassionate. I am always in the best of hands.
- 5 out of 5 starsReviewed on 3/19/2026
I appreciate Dr. Holubars candor. He tells it like it iis. No beating around the bush.
- 5 out of 5 starsReviewed on 3/12/2026
I''m not very good at recalling details. It felt great to know I was in expert care and a plan comes together later
- 5 out of 5 starsReviewed on 3/12/2026
Dr. Holubar is the magician of bowel surgery. I went in thinking I would end up with an opelaparotomy , and woke up with just laparoscopy scars! So pleased with my outcome. A very skilled surgeon.
- 5 out of 5 starsReviewed on 3/12/2026
Dr. Holubar listenened very well to my post op course. Ordered same day testing And I found out I have severe iron deficiency anemia.
- 5 out of 5 starsReviewed on 3/3/2026
Dr Holubar made me feel at ease and in good hands.
- 5 out of 5 starsReviewed on 2/23/2026
I always feel listened to with Dr Holubar.
- 5 out of 5 starsReviewed on 2/23/2026
Dr Holubar and his staff create Excellence in care.
- 5 out of 5 starsReviewed on 2/10/2026
It's a good feeling when the Dr. Is familar with the problem, when he has the same affliction.
- 5 out of 5 starsReviewed on 1/28/2026
Dr Holubar rates excellence !
- 5 out of 5 starsReviewed on 1/28/2026
Dr. Holubar shows a genuine interest in my health and makes me feel good about my visit. He addresses all of my concerns.
- 5 out of 5 starsReviewed on 12/26/2025
Dr Holubar is an excellent role model for colleagues. Excellent communication skills, and heart!
- 5 out of 5 starsReviewed on 12/26/2025
Dr. Holubar listens well and takes on cases no one else will. He is very positive and has a plan for each individual's situation.
- 5 out of 5 starsReviewed on 12/26/2025
Excellent physician & staff!!
- 5 out of 5 starsReviewed on 12/2/2025
Dr. Hulubar and staff were amazing.
- 5 out of 5 starsReviewed on 11/7/2025
Great experience, amazing facility, highly educated doctors and staff.
- 5 out of 5 starsReviewed on 11/7/2025
Great dialogue with provider
- 5 out of 5 starsReviewed on 9/8/2025
Best Dr.
- 5 out of 5 starsReviewed on 8/27/2025
This was my first time meeting Dr. Holubar in person and I liked the way he relates/engages with his patients.
- 5 out of 5 starsReviewed on 8/27/2025
I was very impressed with my office visit and appreciate Dr. Holubar's thoroughness with my situation.
- 5 out of 5 starsReviewed on 6/10/2025
Love my doctor and th
- 5 out of 5 starsReviewed on 5/22/2025
Dr. Holubar made me feel seen and heard.
- 5 out of 5 starsReviewed on 5/12/2025
Dr Holubar and his Fellow were easy to talk to and I felt at ease leaving