Highlights
Age Groups Seen
- Adult
Languages
- English
Gender
MaleAbout Steven Nissen
Biography
Steven Nissen, MD, is Chief Academic Officer, Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute, and holds the Lewis and Patricia Dickey Chair in Cardiovascular Medicine.
Dr. Nissen was Chairman of the Robert and Suzanne Tomsich Department of Cardiovascular Medicine from 2006 to 2019 after serving nine years as Vice Chairman of the Department of Cardiology and five years as Medical Director of the Cleveland Clinic Cardiovascular Coordinating Center (C5), an organization that directs multicenter clinical trials.
Dr. Nissen’s research during the last two decades has focused on the application of intravascular ultrasound (IVUS) imaging to study the progression and regression of coronary atherosclerosis. He has served as International Principal Investigator for several large IVUS multicenter atherosclerosis trials.
Specialty/Clinical interests: General cardiology, intravascular ultrasound (IVUS), diabetes and the heart, drug safety, coronary intensive care
Experience: Dr. Nissen has more than 35 years of experience as a physician. He is world-renowned for his work as a cardiologist, patient advocate and researcher. Equally as significant is his pioneering work in IVUS technology and its use in patients with atherosclerosis.
Publications and Speaking: Dr. Nissen has written more than 400 journal articles and 60 book chapters, including many published in the New England Journal of Medicine and the Journal of the American Medical Association. In recent years, he has also written on the subject of drug safety and was the author of manuscripts highlighting concerns about medications such as Vioxx™, Avandia™, and muraglitazar.
He has testified in both the Senate and the House of Representatives on the topic of drug safety as well as the need to reform the Food and Drug Administration (FDA).
As a physician/scientist, Dr. Nissen is often called on by pharmaceutical companies to consult on the development of new therapies for cardiovascular disease. He maintains a long-standing personal policy that requires these companies to donate all related honoraria directly to charity.
Dr. Nissen is currently the editor of Current Cardiology Report. In 2007, he was listed as Time Magazine 100 Most Influential People in the World – Scientists and Thinkers."
He is heavily involved with the American College of Cardiology (ACC), serving as President from March 2006 to March 2007, a member of the ACC Executive Committee from 2004 to 2008, and spending 10 years as a member of the organization’s Board of Trustees. In addition, Dr. Nissen has served several terms on the Program Committee for the ACC Annual Scientific Sessions.
Dr. Nissen served as a member of the CardioRenal Advisory Panel of Food and Drug Administration (FDA) for five years, and as chair of the final year of his membership. He continues to serve as a periodic advisor to several FDA committees as a Special Government Employee.
Dr. Nissen frequently lectures at national and international meetings. He has served as visiting professor, or provided Grand Rounds, at nearly 100 institutions.
About Dr. Nissen: “I am fiercely independent and don't accept compensation from industry for consulting or speaking.
Leisure time activities: In his leisure time, Dr. Nissen likes to bicycle whenever possible. He is also an advanced amateur photographer.
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Education & Board Certifications
Education
- Fellowship: University of Kentucky Chandler Medical Center, 1983
- Residency: University of California Davis Medical Center, 1981
- Internship: University of California Davis Medical Center, 1979
- Medical Education: University of Michigan Medical School, 1978
- Undergraduate: University of Michigan, 1974
Board Certifications
- Cardiovascular Disease: American Board of Internal Medicine, 1983
- Internal Medicine: American Board of Internal Medicine, 1981
Professional Highlights
- Principal Investigator, Global Cardiovascular Innovation Center, Cleveland Clinic, 2006
- Director, Joseph J. Jacobs Center for Thrombosis and Vascular Biology, Cleveland Clinic
- Member, National Institutes of Health Level 1 Working Group on Clinical Trial Design National Heart, Lung, and Blood Institute (NHLBI), 2006
- National Government Service: Presently serves as Special Government Employee as periodic advisor to the U.S. Food and Drug Administration (FDA).
- Chairman, Cardiovascular Renal Drugs Advisory Committee, Department of Health and Human Resources, FDA, 2004 - 2005
- Member, Cardiovascular Renal Drugs Advisory Committee, Department of Health and Human Resources, FDA, 2000 - 2004
- Medical Director, Cleveland Clinic Cardiovascular Coordinating Center - an organization that directs multicenter clinical trials, 2001 - 2006
Additional Training
- Intensive Care Units Committee, University of Kentucky Medical Center, 1983-1992
- Aeromedical Patient Care for the University of Kentucky, 1987-1992
- Certification - Cardiovascular Medicine, American Board of Internal Medicine, 1983
- Certification - American Board of Internal Medicine, 1979
- Certification - National Board of Medical Examiners, 1979
Awards
- Best Doctors, Cleveland Magazine, 2008, 2014
- America Top Doctors, Castle Connolly, 2014
- Golden Achievement for Medicine Award, Golden Age Centers of Greater Cleveland, 2012
- Simon Dack Award for Outstanding Scholarship, Awarded by Journal of American College of Cardiology Editorial Board and the American College of Cardiology, 2011
- Most Interesting People, Cleveland Magazine, 2010
- 100 Most Influential People in the World Scientists and Thinkers, TIME Magazine, 2007
- Country 30 Most Powerful Forces in Business and Finance, Smart Money, 2007
- President, American College of Cardiology, a 34,000-member, non-profit, professional medical society whose mission is to advocate for quality cardiovascular care - through education, research promotion, development and application of standards and guidelines - and to influence health care policy, March 2006 thru March 2007
- Honorary Member of the Japanese College of Cardiology (JCC), 2007
- Award for Outstanding Contributions to Cardiovascular Research from the Gill Heart Institute of the University of Kentucky, 2004
- Outstanding Scientist Award, Cleveland Clinic, 2004
- Three-time recipient of the Outstanding Teacher Award, Fellows of Cardiovascular Medicine at Cleveland Clinic (2004, 1998, 1994)
- Dr. Nissen has received a number of additional honors and recognitions
Innovations & Patents
- Intravascular ultrasound (IVUS) and application to patients with atherosclerosis. Dr. Nissen has served as principal investigator for 6 major trials using IVUS to assess coronary disease and is currently conducting several additional atherosclerosis studies.
- Co-chairman, American College of Cardiology and the European Society of Cardiology International Writing Group to develop an Expert Consensus Document on Standards for the Acquisition, Measurement, and Reporting of Intravascular Ultrasound Studies, 1999-2001.
- Member, National Joint Committee of the American College of Cardiology and the American Heart Association to revise 1990 Coronary Angiography Guidelines, 1995-2000.
- Appointed committee member in the development of CD-ROM Version of the American College of Cardiology Self-Assessment Program (ACC-SAP), 1994-1996.
- Co-chairman, Joint Committees of the American College of Cardiology and National Electronics Manufacturers Association for Digital Imaging and Communication for Medicine (DICOM) Working Group I, Task Force to Develop Standards for Digital Image Archiving Devices for Cardiac Catheterization Laboratories, 1992-2000.
Research & Publications
See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)
Industry Relationships
Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.
As of 2025-07-03, Dr. Nissen has reported no financial relationship with industry that is applicable to this listing.
In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.
Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.
* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.
Insurances Accepted
Video
Ratings & Reviews
5 out of 5
63 ratings, 20 reviewsThe Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
- 5 out of 5 starsReviewed on 4/27/2026
Dr. Nissen was professional, warm and I appreciated his feedback.
- 5 out of 5 starsReviewed on 4/16/2026
Every time I visit, Dr. Nissen reminds me to keep up the good work to ensure I don''t die of cardi-vascular issues.
- 5 out of 5 starsReviewed on 4/7/2026
Dr. Nissen was clear in discussing the advantages of medical care at the Clinic.
- 5 out of 5 starsReviewed on 4/7/2026
Care was exceptional. I came to see Dr. Nissen because he is one of the world''s experts on heart disease in the setting of elevated LipoProteinA. He addressed all my issues and concerns and explained things in detail. I ma very pleased I traveled two hours to come to see him.
- 5 out of 5 starsReviewed on 3/11/2026
He is the very best and the reason my heart and other related issues are cared for for almost 30 years. He''s the reason my numbers are so good.
- 5 out of 5 starsReviewed on 3/11/2026
Dr Nissen is always aware of what''s going on with me and actually knows who needs to be seen and when.
- 5 out of 5 starsReviewed on 2/3/2026
Best doctor I have ever seen. So knowledgeable and shows true concern. Great confidence in him.
- 5 out of 5 starsReviewed on 2/3/2026
Dr Nissen is excellent in all ways. Highly recommended
- 5 out of 5 starsReviewed on 2/3/2026
Highly recommend. I had an amazing experience with my provider
- 5 out of 5 starsReviewed on 1/14/2026
Dr.Nissen continues to provide personable and professional medical care. In addition,Dr.Nissen values patient input.
- 5 out of 5 starsReviewed on 1/12/2026
Dr. Nissen is the best. He is very thorough and calming. He diagnosed a very rare condition and has helped get the treatment necessary to stabilize my condition.
- 5 out of 5 starsReviewed on 1/12/2026
Dr Nissen was fantastic!
- 5 out of 5 starsReviewed on 1/12/2026
I hope Dr. Nissen never retires! He is a resource that cannot be replaced. I hope he has Apprentices in training.
- 5 out of 5 starsReviewed on 10/21/2025
Wonderful doctor
- 5 out of 5 starsReviewed on 10/21/2025
Wonderful doctor, you can't find a better knowledgeable doctor anywhere like him
- 5 out of 5 starsReviewed on 10/6/2025
Dr. Nissen is GOD
- 5 out of 5 starsReviewed on 9/15/2025
Took a very long time to get in to see doctor.
- 5 out of 5 starsReviewed on 8/20/2025
Dr. Nissen was outstanding,
- 5 out of 5 starsReviewed on 5/22/2025
Dr Nissen is the best provider I've ever seen in my entire medical journey.
- 5 out of 5 starsReviewed on 5/20/2025
Great respectful doctor