Highlights
Age Groups Seen
- Adult
Languages
- English
Gender
MaleLocations
- Hillcrest Medical Building Atrium
- 6770 Mayfield Road, Mayfield Hts, OH 44124
- Get Directions
- Hillcrest Hospital
- 6780 Mayfield Road, Mayfield Hts, OH 44124
- Get Directions
- Twinsburg Family Health and Surgery Center
- 8701 Darrow Road, Twinsburg, OH 44087
- Get Directions
- Mentor Hospital
- 8300 Norton Parkway, Mentor, OH 44060
- Get Directions
Education & Board Certifications
Education
- Internship: Mount Sinai Medical Center of Cleveland
- Residency: Mount Sinai Medical Center (Closed), 1990
- Medical Education: Medical College of Wisconsin, 1985
- Undergraduate: University of Wisconsin, 1981
Board Certifications
- General Surgery: American Board of Surgery, 1991
Professional Memberships
Research & Publications
See publications for this provider. (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)
Industry Relationships
Cleveland Clinic physicians and scientists collaborate with industry to advance medical breakthroughs. These partnerships help commercialize discoveries for public benefit while maintaining scientific integrity. To ensure transparency and minimize potential bias, Cleveland Clinic reviews these relationships and publicly discloses when physicians/scientists receive significant compensation for consulting, serve in fiduciary roles, receive royalties, or hold equity interests related to their work. We manage potential conflicts through approval processes, annual reporting, and targeted management plans.
As of 2025-10-03, Dr. O'Brien has reported no financial relationship with industry that is applicable to this listing.
In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.
Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.
* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.
Insurances Accepted
Video
Ratings & Reviews
4.9 out of 5
152 ratings, 22 reviewsThe Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
- 5 out of 5 starsReviewed on 2/24/2026
Dr. O''Brien is a very excellent Dr. Very professional doing our Appt. Staff very nice.
- 5 out of 5 starsReviewed on 1/14/2026
Dr. O'Brien is an excellent, highly intelligent and caring physician.
- 5 out of 5 starsReviewed on 12/22/2025
Love Dr O'Brien!
- 5 out of 5 starsReviewed on 12/9/2025
Excellent doctor. Professional, knowledgeable, friendly.
- 5 out of 5 starsReviewed on 12/9/2025
Dr O 'Brienis a perfect example of what a Dr should be like.He was very friendly and took his time with us.Seemed very concerned about my issue.He is a model Dr and should be job shadowed by interns he see how to show compassion.You can pass this on to the Dr so he knows he was appreciated. Lou O'Neill
- 5 out of 5 starsReviewed on 11/18/2025
I felt O'Brien was as concerned and involved with me and my situation as any physician that has ever treated me, and I have had some excellent care in the past.
- 5 out of 5 starsReviewed on 10/23/2025
Dr. O'Brian is great!
- 5 out of 5 starsReviewed on 10/23/2025
Dr O'Brian was one of the best doctors I have met with yet. Great personality, very thorough, answered all my questions, and I didn't feel rushed. He's a great doctor.
- 5 out of 5 starsReviewed on 10/8/2025
Dr William O'Brien took his time in answering all are questions. Was very professional Would recommend him.
- 5 out of 5 starsReviewed on 10/8/2025
A most relatable doctor, very collaborative, responsive, and thorough.
- 5 out of 5 starsReviewed on 8/28/2025
I was very impressed with Dr o'Brien.
- 5 out of 5 starsReviewed on 8/28/2025
Excellent doctor!
- 5 out of 5 starsReviewed on 8/19/2025
Excellent on every way. Dr Obrien is fabulous, explaining everything, listens well, clear decisions that make sense!
- 5 out of 5 starsReviewed on 7/22/2025
Very satisfied with finding me the right doctor for me
- 5 out of 5 starsReviewed on 7/8/2025
Dr William O'Brien took his time & answered all of our questions He was excellent!!!
- 5 out of 5 starsReviewed on 6/24/2025
Dr O'Brien had excellent bedside manners. Introduced himself, shook my had and made me feel very comfortable m. Would definitely recommend him
- 5 out of 5 starsReviewed on 6/24/2025
Dr. O'Brien is a top notch surgeon (he operated on my husband's hernia) but he's also one of the good guys. His bedside manner is great and he really makes you feel listened to . I would recommend him to anyone!
- 5 out of 5 starsReviewed on 5/29/2025
Doctor O'Brien was courteous, professional, and explained my condition to me in a way that I understood.
- 5 out of 5 starsReviewed on 5/22/2025
Dr O'Brien was excellent in regards to answering all of my questions and providing recommendations. He was very kind as well as professional and extremely helpful with his recommendations for next steps with the problems I am experiencing
- 5 out of 5 starsReviewed on 5/13/2025
Smooth, cordial experience all the time with the staff. Dr. Obrien was perfect @ Hoghly informative, patient in conversation and a great listener!
- 5 out of 5 starsReviewed on 5/13/2025
The office was extremely friendly! Dr.O'Brian was very informative and without hesitation answered all of our questions.
- 5 out of 5 starsReviewed on 4/28/2025
Dr O'Brien is a great doctor. He listens and explains everything. Very caring and understanding. He listened to my input and we came up with a plan together.